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CUL5 Antibody

ArtNr CSB-PA835890ESR1HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CUL 5 antibody; CUL-5 antibody; CUL5 antibody; CUL5_HUMAN antibody; Cullin 5 antibody; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody; Cullin-5 antibody; Cullin5 antibody; VACM 1 antibody; VACM-1 antibody; VACM1 antibody; Vasopressin activated calcium mobilizing receptor 1 antibody; Vasopressin activated calcium mobilizing receptor antibody; Vasopressin-activated calcium-mobilizing receptor 1 antibody; Vasopressin-activated calcium-mobilizing receptor-1 antibody
Similar products CUL5, VACM1, Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
CUL5
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
CUL 5 antibody; CUL-5 antibody; CUL5 antibody; CUL5_HUMAN antibody; Cullin 5 antibody; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody; Cullin-5 antibody; Cullin5 antibody; VACM 1 antibody; VACM-1 antibody; VACM1 antibody; Vasopressin activated calcium mobilizing receptor 1 antibody; Vasopressin activated calcium mobilizing receptor antibody; Vasopressin-activated calcium-mobilizing receptor 1 antibody; Vasopressin-activated calcium-mobilizing receptor-1 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Cullin-5 protein (1-300AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
Background
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human Cullin-5 protein (1-300AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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