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Recombinant Human Neurotrophin-3(NTF3) (Active)

ArtNr CSB-AP003801HU-50
Hersteller Cusabio
Menge 50 ug
Quantity options 1 mg 10 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized powder
Specific against Human (Homo sapiens)
Purity Greater than 95% as determined by SDS-PAGE.
Sequence YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQV TVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGI DDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRID TSCVCALSRKIGRT
Protein Familie NGF-beta family
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3
Lieferbar
Manufacturer - Category
Cytokine / Growth Factor
Manufacturer - Conjugate / Tag
Tag-Free
Molecular Weight
13.6 kDa
General Research Areas
Neuroscience
Relevance
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to beta-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.
Function
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Subcellular Location
Secreted
Tissue Specificity
Brain and peripheral tissues.
Paythway
MAPKsignalingpathway
Gene Names
NTF3
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer
Lyophilized from a 0.2 um filtered 20 mM PB, 250 mM NaCl, pH 7.2
Expression Region
139-257aa
Protein Description
Full Length of Mature Protein
Biological Activity
The ED50 as determined by its ability to bind Human NTRK2 in functional ELISA is less than 10 ug/ml.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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