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Recombinant Human Leukemia inhibitory factor protein(LIF) (Active)

Recombinant Human Leukemia inhibitory factor protein(LIF) (Active)

ArtNr	CSB-AP002221HU-100
Hersteller	Cusabio
Menge	100 ug
Quantity options	1 mg 100 ug 25 ug 250 ug 5 ug 500 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins By Organ Skin Cancer Heart & Blood Cancer
Typ	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>98% as determined by SDS-PAGE and HPLC.
Sequence	SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQ LNGSANAL FILYYTAQGE PFPNNLDKLC GPNV TDFPPF HANGTEKAKL VELYRIVVYL GTSLGN ITRD QKILNPSALS LHSKLNATAD ILRGLLSN VL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
Protein Familie	LIF/OSM family
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LIF, D factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin
Lieferbar
Manufacturer - Category	Cytokine / Growth Factor
Manufacturer - Conjugate / Tag	Tag-Free
Molecular Weight	19.7 kDa
General Research Areas	Immunology
Relevance	LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Function	LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Subcellular Location	Secreted
Paythway	Jak-STATsignalingpathway
Gene Names	LIF, HILDA
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Uniprot Entry Name	LIF_HUMAN
Expression Region	23-202aa
Protein Description	Full Length of Mature Protein
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent proliferation of human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
PubMed ID	3143918; 2475312; 15146197; 1692837; 14702039; 10591208; 15489334; 3128791; 2730639; 8489250; 14527405; 17652170

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-AP002221HU-100-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 2 Tage sparen

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