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Recombinant Mouse [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial (Pdk3),partial

Recombinant Mouse [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial (Pdk3),partial

ArtNr	CSB-EP852852MO-1
Hersteller	Cusabio
Menge	1 mg
Quantity options	1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Konjugat/Tag	HIS
Purity	Greater than 90% as determined by SDS-PAGE.
Sequence	IEYKEKFGFDPFISSNIQYFLDRFYTNRISFRMLI NQHTLLFGGDTNPAHPKHIGSIDPTCNVADVVKDA YETAKMLCEQYYLVAPELEVEEFNAKAPNKPIQVV YVPSHLFHMLFELFKNSMRATVELHEDKKEGYPAV KTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMY STAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQG DLKLYSMEGVGTDAVIYLKALS
Protein Familie	PDK/BCKDK protein kinase family
Citations	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project Team Genome Res. 14:2121-2127(2004)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Pyruvate dehydrogenase kinase isoform 3;
Lieferbar
Manufacturer - Targets	Pdk3
Manufacturer - Conjugate / Tag	N-terminal 6xHis-tagged
Storage Conditions	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight	30.3 kDa
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
General Research Areas	Signal Transduction
Relevance	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species
Biologically Active	Not Test
Expression Region	131-362aa
Protein Length	Partial
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).
Subcellular Location	Mitochondrion matrix

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CSB-EP852852MO-1-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 1 mg

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Lieferung vsl. bis 28.08.2025

Express-Lieferung: 2 Tage sparen

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