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Recombinant Human Peroxisomal multifunctional enzyme type 2(HSD17B4)

ArtNr CSB-YP010774HU-1
Hersteller Cusabio
Menge 1 mg
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host Yeast
Konjugat/Tag HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGAL VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAV ANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRD RSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKK QKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLA NSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLV EALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIG KLR
Protein Familie Short-chain dehydrogenases/reductases (SDR) family
Citations "The DNA sequence and comparative analysis of human chromosome 5."Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. Rubin E.M.Nature 431:268-274(2004)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 17-beta-hydroxysteroid dehydrogenase 4; Short name:; 17-beta-HSD 4; D-bifunctional protein; Short name:; DBP; Multifunctional protein 2; Short name:; MPF-2; Short chain dehydrogenase/reductase family 8C member 1; Cleaved into the following 2 chains:; (3R)-hydroxyacyl-CoA dehydrogenase (EC:1.1.1.n12); Enoyl-CoA hydratase 2 (EC:4.2.1.107, EC:4.2.1.119); Alternative name(s):; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 6xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
81.7 kDa
General Research Areas
Cancer
Relevance
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids
Expression Region
1-736aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Subcellular Location
Peroxisome
Tissue Specificity
Present in many tissues with highest concentrations in liver, heart, prostate and testis.
Involvement in disease
D-bifunctional protein deficiency (DBPD); Perrault syndrome 1 (PRLTS1)
Gene Names
HSD17B4
Sequence Info
Full Length
Organism
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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