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Recombinant Human Valacyclovir hydrolase(BPHL)

Recombinant Human Valacyclovir hydrolase(BPHL)

ArtNr	CSB-YP774821HU-100
Hersteller	Cusabio
Menge	100 ug
Quantity options	1 mg 10 ug 100 ug 200 ug 50 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Host	Yeast
Konjugat/Tag	Myc, HIS
Purity	Greater than 90% as determined by SDS-PAGE.
Sequence	SVTSAKVAVNGVQLHYQQTGEGDHAVLLLPGMLGS GETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDR DFPADFFERDAKDAVDLMKALKFKKVSLLGWSDGG ITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYE GIRDVSKWSERTRKPLEALYGYDYFARTCEKWVDG IRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLV PRFHADFIHKHVKGSRLHLMPEGKHNLHLRFADEF NKL
Protein Familie	AB hydrolase superfamily, Lipase family
Citations	"Cloning and expression analysis of a novel human serine hydrolase with sequence similarity to prokaryotic enzymes involved in the degradation of aromatic compounds." Puente X.S., Lopez-Otin C. J. Biol. Chem. 270:12926-12932(1995)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Biphenyl hydrolase-like protein (Biphenyl hydrolase-related protein) (Bph-rp)(Breast epithelial mucin-associated antigen) (MCNAA)
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Manufacturer - Targets	BPHL
Manufacturer - Conjugate / Tag	N-terminal 10xHis-tagged and C-terminal Myc-tagged
Storage Conditions	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight	32.8 kDa
General Research Areas	Signal Transduction
Relevance	Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Expression Region	38-291aa
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Tissue Specificity	Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle.
Biologically active	Not Test
Protein length	Full Length of Mature Protein

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Menge: 100 ug

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Lieferung vsl. bis 28.08.2025