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PRKAR2A Polyclonal Antibody

ArtNr E-AB-52196-60
Hersteller Elabscience
Menge 60 uL
Quantity options 120 uL 20 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cAMP dependent protein kinase regulatory subunit alpha 2, cAMP dependent protein kinase regulatory subunit RII alpha, cAMP dependent protein kinase type II alpha regulatory chain, cAMP dependent protein kinase type II alpha regulatory subunit, cAMP-dependent protein kinase type II-alpha regulatory subunit, KAP2, KAP2, MGC3606, PKR 2, PKR2, PRKA R2, PRKAR 2, PRKAR2, PRKAR2A, Protein kinase A RII alpha subunit, Protein kinase cAMP dependent regulatory type II alpha
Similar products PRKAR2A, PKR2, KAP2, MGC3606, PRKAR2, PKR 2, PRKA R2, PRKAR 2, Protein kinase A RII alpha subunit, Protein kinase cAMP dependent regulatory type II alpha, cAMP dependent protein kinase regulatory subunit alpha 2, cAMP dependent protein kinase regulatory subunit RII alpha, cAMP dependent protein kinase type II alpha regulatory chain, cAMP dependent protein kinase type II alpha regulatory subunit, cAMP-dependent protein kinase type II-alpha regulatory subunit
Versandbedingung Gekühlt
Gefahren-Info Comply with cargo safety certificate
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
PRKAR2A
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
Refer to figures
Research Areas
Cancer, Metabolism, Signal Transduction
Background
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Concentration
0.8 mg/mL
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method
Antigen affinity purification
Recommended Dilution
WB 1:500-1:2000; IHC 1:35-1:200
Abbreviation
PRKAR2A
Clonality
Polyclonal
Immunogen
Fusion protein of human PRKAR2A
Category ID III
Polyclonal Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 60 uL
Lieferbar: In stock
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