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UPF1 Polyclonal Antibody

UPF1 Polyclonal Antibody

ArtNr	E-AB-13000-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, FLJ43809, FLJ46894, HUPF 1, hUpf1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Frameshift 1, Up frameshift mutation 1 homolog (S. cerevisiae), Up frameshift mutation 1 homolog, Up frameshift suppressor 1 homolog, Up-frameshift suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, upf1, UPF1 regulator of nonsense transcripts homolog, UPF1 RNA helicase and ATPase, Yeast Upf1p homolog
Similar products	KIAA0221, RENT1, Regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1, Up-frameshift suppressor 1 homolog, upf1, FLJ43809, FLJ46894, NORF1, pNORF1, UP Frameshift 1, ATP dependent helicase RENT1, Delta helicase, HUPF 1, NORF 1, pNORF 1, RENT 1, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UPF 1, UPF 1 regulator of nonsense transcripts homolog, hUpf1, Up frameshift mutation 1 homolog (S. cerevisiae), Up frameshift mutation 1 homolog, Up frameshift suppressor 1 homolog, UPF1 regulator of nonsense transcripts homolog, UPF1 RNA helicase and ATPase, Yeast Upf1p homolog
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	UPF1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	124kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	This gene encodes a protein that is part of a post-splicing multiprotein complex involved in botHuman, MouseRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Concentration	0.1 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000; IHC 1:50-1:200
Santa Cruz #	sc-18258, sc-18259, sc-18260, sc-48802
Abbreviation	UPF1
Clonality	Polyclonal
Immunogen	Synthetic peptide of human UPF1
Category ID III	Polyclonal Antibodies

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