LOXL1 Polyclonal Antibody

63kDa

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to eacHuman, Mouseember of the family.

PBS with 0.05% sodium azide and 50% glycerol, pH 7.4

WB 1:200-1:1000

Synthetic peptide of human LOXL1