HDAC5 Polyclonal Antibody

HDAC5

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

122kDa

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000

HDAC5

Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of Ser498.