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Phospho-CHEK2 (Thr68) Polyclonal Antibody

Phospho-CHEK2 (Thr68) Polyclonal Antibody

ArtNr	E-AB-20843-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Neural Development Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Stem Cell Markers Progenitor Markers
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CDS 1, Cds1, Cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, CHEK 2, Chek2, Chk 2, CHK2 checkpoint homolog (S. pombe), CHK2 checkpoint homolog, CHK2, hCds1, HuCds 1, LFS 2, LFS2, PP1425, RAD 53, RAD53, Rad53 homolog, Serine/threonine protein kinase Chk2, Serine/threonine-protein kinase Chk2
Similar products	Serine/threonine-protein kinase Chk2, Cds1, CHK2, RAD53, LFS2, PP1425, hCds1, CHK2 checkpoint homolog, Cds1 homolog, Checkpoint kinase 2, CDS 1, Checkpoint like protein CHK2, Chek2, Chk 2, HuCds 1, LFS 2, RAD 53, Rad53 homolog, CHEK 2, CHK2 checkpoint homolog (S. pombe), Serine/threonine protein kinase Chk2
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	Chk2 (phospho Thr68)
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	61kDa
Observed Molecular Weight	61kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Abbreviation	Chk2 (phospho Thr68)
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
Category ID III	Acetyl/Phospho/Methyl Antibodies

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