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LMNA Polyclonal Antibody

LMNA Polyclonal Antibody

ArtNr	E-AB-31899-200
Hersteller	Elabscience
Menge	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Intermediate filaments By Organ Breast Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	https://www.sciencedirect.com/science/article/pii/S0898656821000164
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32
Similar products	LMNA, LMN1, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, Lamin A, PRO1, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, LDP1, LFP, LGMD1B, LMNC, Lamin, Lamin A/C, FPLD2, LMNL1, LMN 1, LMN C, LMN A, Lamin C, Cardiomyopathy dilated 1A (autosomal dominant), Lamin A/C like 1, Limb girdle muscular dystrophy 1B (autosomal dominant), Prelamin A/C, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NYREN32
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	Lamin A/C
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	74kDa
Observed Molecular Weight	74kDa, 65kDa
Research Areas	Cancer, Signal Transduction, Tags and Cell Markers
Background	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Abbreviation	Lamin A/C
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.
Category ID III	Polyclonal Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.