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BUB1 Polyclonal Antibody

ArtNr E-AB-60506-120
Hersteller Elabscience
Menge 120 uL
Quantity options 120 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Bub1, BUB1 budding uninhibited by benzimidazoles 1 homolog, BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast), BUB1 mitotic checkpoint serine/threonine kinase, BUB1, S. cerevisiae, homolog of, BUB1, BUB1A, BUB1L, Budding uninhibited by benzimidazoles 1 (yeast homolog), Budding uninhibited by benzimidazoles 1 homolog, Budding uninhibited by benzimidazoles 1, S. cerevisiae, homolog of, hBUB1, Homolog of mitotic checkpoint gene BUB1, Mitotic checkpoint gene BUB1, Mitotic checkpoint serine/threonine protein kinase BUB1, Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle checkpoint kinase, Putative serine/threonine protein kinase
Similar products Bub1, BUB1, BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1A, S. cerevisiae, homolog of, hBUB1, BUB1 budding uninhibited by benzimidazoles 1 homolog, Budding uninhibited by benzimidazoles 1, BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast), BUB1 mitotic checkpoint serine/threonine kinase, Budding uninhibited by benzimidazoles 1 (yeast homolog), Budding uninhibited by benzimidazoles 1 homolog, Homolog of mitotic checkpoint gene BUB1, Mitotic checkpoint gene BUB1, Mitotic checkpoint serine/threonine protein kinase BUB1, Mitotic spindle checkpoint kinase, Putative serine/threonine protein kinase
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Storage Conditions
Store at -20C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
115kDa/120kDa/122kDa
Observed Molecular Weight
133kDa
Research Areas
Cancer, Cell Biology
Background
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Concentration
1 mg/mL
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4
Purification Method
Affinity purification
Recommended Dilution
WB1:500 - 1:2000 IHC1:50 - 1:200
Immunogen
Recombinant protein of human BUB1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 120 uL
Lieferbar: In stock
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