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Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag)

Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag)

ArtNr	ELS-PKSH030316-50ug
Hersteller	Elabscience
Menge	50 ug
Quantity options	20 ug 50 ug
Kategorie	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Enzymes Fatty Acid Catabolism
Typ	Proteins
Format	Liquid
Specific against	Human (Homo sapiens)
Host	Insect Cells, Baculovirus-Infected Insect Cells
Konjugat/Tag	HIS, GST
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Leu 384
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SPHK, SPHK1, SPK
Similar products	SPHK1, SPK, SPHK
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-His-GST
Shipping Temperature	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight	70.3 kDa
Observed Molecular Weight	64 kDa
Research Areas	Signal Transduction, Cancer, Metabolism
Background	SPHK1; also known as sphingosine Kinase 1; catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation; survival; migration; cytoskeletal organization; and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory; antiapoptotic; and immune processes.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Not Applicable
Formulation	Supplied as sterile solution of 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0
Activity	Not validated for activity

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ELS-PKSH030316-50ug-datasheet.pdf

ELS-PKSH030316-50ug-safety-datasheet.pdf