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Recombinant Human BUP1 Protein (His Tag)

ArtNr ELS-PKSH033271-50ug
Hersteller Elabscience
Menge 50 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Met 1-Glu384
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BUP-1, BUP1, Beta-Alanine Synthase, Beta-Ureidopropionase, N-Carbamoyl-Beta-Alanine Amidohydrolase, UPB1
Similar products UPB1, BUP1, BUP-1, Beta-Ureidopropionase, Beta-Alanine Synthase, N-Carbamoyl-Beta-Alanine Amidohydrolase
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Others
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
44.2 kDa
Observed Molecular Weight
42 kDa
Research Areas
Signal Transduction, epigenetics and nuclear signal, metabolism,
Background
β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid, respectively. Defects in β-Ureidopropionase are the cause of β-Ureidopropionase deficiency that is characterized by muscular hypotonia, dystonic movements, scoliosis, microcephaly and severe developmental delay.
Abbreviation
BUP1
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Not Applicable
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Activity
Not validated for activity
Protein Construction
Recombinant Human beta-Ureidopropionase is produced by our E.coli expression system and the target gene encoding Met1-Glu384 is expressed with a 6His tag at the C-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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