Hersteller |
Enogene
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Human |
Applikationen |
ELISA, Western Blot |
Menge |
100ug/100ul |
Host |
Mouse |
ArtNr |
E10-20405 |
Targets |
AFP |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Background |
AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Research Area |
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Form of Antibody |
Ascitic fluid containing 0.03% sodium azide. |
Altername |
alpha-fetoprotein, FETA, HPAFP |
Immunogen |
Purified recombinant fragment of human AFP expressed in E. Coli. |
Applications information |
WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test. |
Molecular Weight |
69kDa |
Recommended Dilutions |
WB 1/500 - 1/2000.ELISA. Propose dilution 1/10000. |
Storage/Stability |
Store at 4C, for long term storage, store at -20C |
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