Manufacturer |
Enogene
|
Category |
|
Type |
Antibody |
Specific against |
Human |
Applications |
ELISA, Western Blot |
Amount |
100ug/100ul |
Host |
Mouse |
Item no. |
E10-20405 |
Targets |
AFP |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Background |
AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Research Area |
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Form of Antibody |
Ascitic fluid containing 0.03% sodium azide. |
Altername |
alpha-fetoprotein, FETA, HPAFP |
Immunogen |
Purified recombinant fragment of human AFP expressed in E. Coli. |
Applications information |
WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test. |
Molecular Weight |
69kDa |
Recommended Dilutions |
WB 1/500 - 1/2000.ELISA. Propose dilution 1/10000. |
Storage/Stability |
Store at 4C, for long term storage, store at -20C |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.