SNAI2 Antibody

WB, ELISA. Not yet tested in other applications.

Store at 4C, for long term storage, store at -20C.

Purified recombinant fragment of human SNAI2 expressed in E. Coli.

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Ascitic fluid containing 0.03% sodium azide.