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Phospho-AKT1(Thr308) Antibody

Phospho-AKT1(Thr308) Antibody

ArtNr	E18-0832-2
Hersteller	Enogene
Menge	100 ug/100 ul
Quantity options	50 ug/50 ul 100 ug/100 ul
Kategorie	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies
Typ	Antibody
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1
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Specificity	Phospho-AKT1(Thr308) Antibody detects endogenous levels of AKT1 only when phosphorylated at Threonine 308
Manufacturer - Applications	WB 1:500-1:2000
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	56-60kDa
Immunogen	A synthesized peptide derived from human AKT1 around the phosphorylation site of Threonine 308
Purification	Immunogen affinity purified
Background	an AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus. Tumorigenic in a mouse lymphoma model and activated (by phospho-Akt staining) and/or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Inhibitor: RX-0201. Substrates include tuberin, Bad, Forkhead transcription factors, caspase-9, and glycogen synthase kinase-3.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0036365

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug/100 ul

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Lieferung vsl. bis 28.08.2025

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