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Lamin A+C Antibody, pAb, Rabbit Europäischer Partner

ArtNr A01455-40
Hersteller GenScript
Menge 40 ug
Quantity options 100 ug 40 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC, other
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), other
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias A01455-Lamin_A_C_Antibody_pAb_Rabbit,Lamin A/C antibody,
Similar products Lamin
Lieferbar
Specificity Human and mouse. This product has not been tested for other species yet.
Manufacturer - Isotype
Rabbit IgG
Country of Origin
USA
Storage Conditions
GenScript Rabbit Anti-Lamin A+C Polyclonal Antibody should be stored lyophilized until use. It remains stable in lyophilized form for at least two years if stored at -20C or below. The reconstituted antibody can be stored for two to three weeks at 2-8C or for up to 12 months at -20C or below. Avoid repeated freeze and thaw cycles.
Manufacturer - Specificity
GenScript Rabbit Anti-Lamin A+C Polyclonal Antibody detects endogenous levels of human and mouse Lamin A and Lamin C. It is predicted to react with rat Lamin A and Lamin C according to sequence homology. Positive Control: Hela, A431, Lovo and NIH/3T3
Concentration
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description
Lamins are structural protein components of the nuclear lamina which contains 3 members: Lamin A, B and C in mammalian cells. Lamin A and lamin C are generated by alternative splicing from the same gene and share complete identity for the first 566 amino acids. Lamin A interacts with transcription factor SREBP1 via its C-terminal domain. The lamin A/C deficiency is probably associated with both defective nuclear mechanics and impaired transcriptional activation. The lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. GenScript, Rabbit Anti-Lamin A+C Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide within residues 400-450 of human Lamin A (Swiss Prot: P02545).
Immunogen
KLH-coupled synthetic peptide within residues 400-450 of human Lamin A (Swiss Prot: P02545).
Purification Method
Immunoaffinity chromatography
Reconstitution
Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 40 ug
Lieferbar: In stock
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Lieferung vsl. bis 13.11.2025 

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