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Lamin A+C Antibody, pAb, Rabbit

Lamin A+C Antibody, pAb, Rabbit

Item no.	A01455-40
Manufacturer	GenScript
Amount	40 ug
Quantity options	100 ug 40 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Sarcoma Cell Biology Cytoskeleton Primary Antibodies Intermediate filaments By Organ Breast Cancer
Type	Antibody Polyclonal
Applications	WB, FC, other
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), other
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01455-Lamin_A_C_Antibody_pAb_Rabbit,Lamin A/C antibody,
Similar products	Lamin
Available
Specificity	Human and mouse. This product has not been tested for other species yet.
Manufacturer - Isotype	Rabbit IgG
Country of Origin	USA
Storage Conditions	GenScript Rabbit Anti-Lamin A+C Polyclonal Antibody should be stored lyophilized until use. It remains stable in lyophilized form for at least two years if stored at -20C or below. The reconstituted antibody can be stored for two to three weeks at 2-8C or for up to 12 months at -20C or below. Avoid repeated freeze and thaw cycles.
Manufacturer - Specificity	GenScript Rabbit Anti-Lamin A+C Polyclonal Antibody detects endogenous levels of human and mouse Lamin A and Lamin C. It is predicted to react with rat Lamin A and Lamin C according to sequence homology. Positive Control: Hela, A431, Lovo and NIH/3T3
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	Lamins are structural protein components of the nuclear lamina which contains 3 members: Lamin A, B and C in mammalian cells. Lamin A and lamin C are generated by alternative splicing from the same gene and share complete identity for the first 566 amino acids. Lamin A interacts with transcription factor SREBP1 via its C-terminal domain. The lamin A/C deficiency is probably associated with both defective nuclear mechanics and impaired transcriptional activation. The lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. GenScript, Rabbit Anti-Lamin A+C Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide within residues 400-450 of human Lamin A (Swiss Prot: P02545).
Immunogen	KLH-coupled synthetic peptide within residues 400-450 of human Lamin A (Swiss Prot: P02545).
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 40 ug

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Delivery expected until 11/13/2025

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