Interferon-gamma (IFN-gamma), Human

Hersteller GenScript
Kategorie Produkte / Proteins
Typ Proteins
Specific against Human
Menge 10ug
ArtNr Z02986-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokines, Chemokines & Growth Factors
Description
Human Interferon gamma (hIFN-gamma), is amacrophage-activating factor and the lone member of Interferon type II. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
M.W.
15-25 kDa, observed by non-reducing SDS-PAGE.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 5x105 units/mg.
Storage
Lyophilized recombinant, Human Interferon gamma (IFN-gamma), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rh IFN-gamma should be stable up to 1 week at 4C or up to 2 months at -20C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Sequence
Gln24 -Gln166 (Accession # CAA31639).
Note
For research use only
Menge: 10ug
Lieferbar: In stock
Listenpreis: 27,36 €
Preis: 27,36 €
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