Epidermal Growth Factor (EGF), Mouse

Hersteller GenScript
Kategorie Produkte / Proteins
Typ Proteins
Specific against Mouse
Menge 10ug
ArtNr Z02972-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokines, Chemokines & Growth Factors
Description
Epidermal Growth Factor (EGF), was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor). Recombinant, mouse Epidermal Growth Factor (rmEGF), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rmEGF is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 6.2kDa analyzed by reducing SDS-PAGE.
M.W.
6.2 kDa, observed by reducing SDS-PAGE.
Purity
> 95% by SDS-PAGE and HPLC analysis.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 1.0x 107units/mg.
Storage
Lyophilized recombinant, mouse Epidermal Growth Factor (rmEGF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmEGF should be stable up to 2 weeks at 4C or up to 3 months at -20C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Sequence
Asn977-Arg1029 (accession number:P01132), expressed with an N-terminal Met.
Note
For research use only
Menge: 10ug
Lieferbar: In stock
Listenpreis: 16,35 €
Preis: 16,35 €
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