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EGF, Mouse Europäischer Partner

ArtNr Z02972-10
Hersteller GenScript
Menge 10 ug
Quantity options 1 mg 10 ug 50 ug
Kategorie
Typ Proteins
Specific against Mouse (Murine, Mus musculus)
Purity > 95% by SDS-PAGE and HPLC analysis.
Sequence Asn977-Arg1029 (accession number:P01132), expressed with an N-terminal Met.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02972_10-Epidermal_Growth_Factor_EGF_Mouse,Epidermal Growth Factor (EGF), was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor). Recombinant, mouse Epidermal Growth Factor (rmEGF), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rmEGF is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 6.2kDa analyzed by reducing SDS-PAGE.</td></tr><tr><th>M.W.</th><td colspan="7"> 6.2 kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analysis.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 1.0× 107units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, mouse Epidermal Growth Factor (rmEGF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmEGF should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Asn977-Arg1029 (accession number:P01132), expressed with an N-terminal Met.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products Epidermal
Versandbedingung Gekühlt
Lieferbar
Specificity ED50, 1.0x 107units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
6.2 kDa, observed by reducing SDS-PAGE.
Product Line
Growth Factors
Manufacturer - Specificity
ED50, 1.0x 107units/mg.
Description
Epidermal Growth Factor (EGF), was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor). Recombinant, mouse Epidermal Growth Factor (rmEGF), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rmEGF is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 6.2kDa analyzed by reducing SDS-PAGE.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Notes
For research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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