Interleukin-1 Beta (IL-1 Beta), Mouse

Hersteller GenScript
Typ Proteins
Specific against Mouse
Menge 1.0mg
ArtNr Z02985-1
eClass 6.1 34160400
eClass 9.0 42020190
Product Line
Cytokines, Chemokines & Growth Factors
Interleukin-1 Beta (IL-1beta), is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. Recombinant, mouse Interleukin-1 Beta(rmIL-1beta), produced in E. coli is a single non-glycosylated polypeptide chain containing 153 amino acids. A fully biologically active molecule, rmIL-1beta is obtained by proprietary chromatographic techniques at GenScript, with an apparent molecular weight of 17.5kDa analyzed by reducing SDS-PAGE.
17.5kDa, observed by reducing SDS-PAGE.
> 95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 5.0x 108units/mg.
Lyophilized recombinant, mouseInterleukin-1 Beta(rmIL-1beta), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmIL-1beta should be stable up to 2 weeks at 4C or up to 3 months at -20C.
Lyophilized after extensive dialysis against PBS.
Reconstituted in ddH2O or PBS at 100 ug/ml.
Val118-Ser269 (accession number:P10749), expressed with an N-terminal Met.
For research use only
Menge: 1.0mg
Lieferbar: In stock
Listenpreis: 1.872,75 €
Preis: 1.872,75 €


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