Interferon-gamma ( IFN-gamma), Rat

Hersteller GenScript
Typ Proteins
Specific against Rat
Menge 10ug
ArtNr Z02982-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Product Line
Cytokines, Chemokines & Growth Factors
Interferon-gamma (IFN-gamma), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
15-25 kDa, observed by non-reducing SDS-PAGE.
> 95% as analyzed by SDS-PAGE and HPLC.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 4x105 units/mg.
Lyophilized recombinant, Rat Interferon gamma (IFN-gamma), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rrIFN-gamma should be stable up to 1 week at 4C or up to 2 months at -20C.
Lyophilized after extensive dialysis against PBS.
Reconstituted in ddH2O or PBS at 100 ug/ml.
Glu23-Cys156 (Accession # P01581).
For research use only
Menge: 10ug
Lieferbar: In stock
Listenpreis: 30,10 €
Preis: 30,10 €

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