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Risedronic acid (sodium)

Risedronic acid (sodium)

ArtNr	HY-B0119-1g
Hersteller	MedChem Express
CAS-Nr.	115436-72-1
Menge	1 g
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg
Kategorie	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Testicular & Prostate Cancer
Typ	Inhibitors
Specific against	other
Purity	99.72
Citations	[1]Fujita H, et al. Effect of risedronate on osteoblast differentiation, expression of receptor activator of NF-κB ligand and apoptosis in mesenchymal stem cells. Basic Clin Pharmacol Toxicol. 2011 Aug;109(2):78-84. \|[2]Jordao FM, et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31.\|[3]Willey JS, et al. Risedronate prevents early radiation-induced osteoporosis in mice at multiple skeletal locations. Bone. 2010 Jan;46(1):101-11.
Smiles	OC(P(O)(O[Na])=O)(P(O)(O)=O)CC1=CN=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Risedronate (sodium)
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Targets	Apoptosis; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	305.09
Product Description	Risedronic acid (Risedronate) sodium, a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid sodium inhibits blood stages of Plasmodium falciparum (IC50 of 20.3 μM). Risedronic acid sodium inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Metabolic Disease
Solubility	DMSO: < 1 mg/mL\|H2O: 8.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis
Clinical information	Launched

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HY-B0119-1g-safety-datasheet.pdf