Pantethine

ArtNr	HY-B1028-5g
Hersteller	MedChem Express
CAS-Nr.	16816-67-4
Menge	5 g
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.91
Citations	[1]Bocos C, et al. Pantethine stimulates lipolysis in adipose tissue and inhibits cholesterol and fatty acid synthesis in liver and intestinal mucosa in the normolipidemic rat. Environ Toxicol Pharmacol. 1998 Aug 4;6(1):59-66.\|[2]Abou-Hamdan M, et al. Potential antiviral effects of pantethine against SARS-CoV-2. Sci Rep. 2023 Feb 8;13(1):2237. \|[3]Penet MF, et al. Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism. Front Oncol. 2016 Nov 16;6:244. \|[4]Tóth F, et al. Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid. Int J Mol Sci. 2021 Jan 2;22(1):403.\|[5]Kavian N, et al. Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding. Arthritis Rheumatol. 2015 Jul;67(7):1881-90.\|[6]Brunetti D, et al. Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model. Brain. 2014 Jan;137(Pt 1):57-68.
Smiles	O=C(NCCSSCCNC(CCNC([C@H](O)C(C)(C)CO)=O)=O)CCNC([C@H](O)C(C)(C)CO)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	D-Pantethine,LBF disulfide
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Targets	Endogenous Metabolite; SARS-CoV
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	554.72
Product Description	Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration[1][2][3][4][5][6].
Manufacturer - Research Area	Cancer; Endocrinology; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Solubility	DMSO: ≥ 100 mg/mL\|Ethanol: 100 mg/mL (ultrasonic)\|H2O: ≥ 100 mg/mL
Manufacturer - Pathway	Anti-infection; Metabolic Enzyme/Protease
Clinical information	Phase 3

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HY-B1028-5g-safety-datasheet.pdf