Glucosamine

ArtNr	HY-B1125-5mg
Hersteller	MedChem Express
CAS-Nr.	3416-24-8
Menge	5 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 25 mg 50 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Bruyère O, et al. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S12-7.\|[2]Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.\|[3]Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706.\|[4]Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84. Int Immunopharmacol. 2024 Oct 18;143(Pt 2):113427.\|Microbiome. 2019 Mar 20;7(1):43. \|Nature. 2024 Dec 18.\|Theranostics. 2021 Mar 24;11(12):5650-5674.\|Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.
Smiles	O=C[C@H](N)[C@H]([C@@H]([C@@H](CO)O)O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	D-Glucosamine,Chitosamine
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Autophagy; CFTR; Endogenous Metabolite; HIF/HIF Prolyl-Hydroxylase; Reactive Oxygen Species (ROS)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	179.17
Product Description	Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO: 3.33 mg/mL (ultrasonic)\|H2O: 100 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Autophagy; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB
Isoform	Human Endogenous Metabolite
Clinical information	Launched

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HY-B1125-5mg-safety-datasheet.pdf