FICZ

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM*1mL (in DMSO)
ArtNr HY-12451-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
6-Formylindolo[3, 2-b]carbazole
CAS No.
172922-91-7
Purity
>98%
MW
2843114
Formula
C19H12N2O
Solubility
DMSO: 10 mg/mL
Biological Description
FICZ(6-Formylindolo[3, 2-b]carbazole) is a tryptophan-derived, high affinity Ah receptor ligand; efficient inducer of CYP1A1 gene expression in short time incubation (0.5 h) experiments.
IC50 value:
Target: Ah receptor ligand
FICZ caused increased mRNA levels already at a concentration of 100 pM. FICZ was also shown to increase CYP1A1 mRNA levels in fresh human peripheral blood cells at the same low concentration. FICZ and ICZ were furthermore compared with regard to their capacity to inhibit cDNA-expressed human CYP1A1 enzyme and FICZ was found to be the most potent inhibitor [1].
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 380,00 €
Preis: 380,00 €
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