Adenosine-5'-(γ-thio)-triphosphate tetralithium salt

Blue Ice

551

White solid

Adenosine 5’-[γ-thio]triphosphate Tetralithium Salt is used as a reagent in the synthesis of DNA N-acetylglucosamine analogs. Adenosine 5'-(γ-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11).1 It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs, and can serve as a substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eukaryotic initiation factor-4A.

Synonyms:
ATP-γS; ATPγS tetralithium salt

CAS Number:
93839-89-5

Molecular Formula:
C₁₀H₁₆N₅O₁₂P₃SLi₄

Molecular Weight:
551

Appearance:
White solid

Purity:
≥90% (HPLC)

Melting Point:
>232°C (dec.)

Solubility:
Water

Storage:
-20°C