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Recombinant mouse RANK/TNFRSF11A protein

ArtNr NKM-ATGP4155-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADL>VTPPCTQ ERHYEHLGRC CSRCEPGKYL SSKCTPTSDS VCLPCGPDEY LDTWNEEDKC LLHKVCDAGK ALVAVDPGNH TAPRRCACTA GYHWNSDCEC CRRNTECAPG FGAQHPLQLN KDTVCTPCLL GFFSDVFSST DKCKPWTNCT LLGKLEAHQG TTESDVVCSS SMTLRRPPKE AQAYLPS<LEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP
Citations Anderson, D.M. et al. (1997) Nature 390, 175-179.
Nakagawa, N. et al. (1998) Biochem. Biophys. Res. Commun. 245:395-400.
Bharat B. Aggarwal. (2003) Nature 3, 745-756.
NCBI NP_033425.3
Alias TNF receptor superfamily member 11a,Tumor necrosis factor receptor superfamily member 11A,Osteoclast differentiation factor receptor,Receptor activator of NF-KB,Familial expansile osteolysis,TRANCE receptor,RANK,CD265,FEO,ODFR,TRANCE-R,TNR11
Similar products ATGP4155-10ug, ATGP4155-20ug, ATGP4155-50ug, ATGP4155-100ug, ATGP4155-250ug, ATGP4155-500ug, ATGP4155-1mg, ATGP4155-010, ATGP4155-020, ATGP4155-050, ATGP4155-100, ATGP4155-250, ATGP4155-500, ATGP4155-01M, ATGP3939-10ug, ATGP3939-20ug, ATGP3939-50ug, ATGP3939-100ug, ATGP3939-250ug, ATGP3939-500ug, ATGP3939-1mg, ATGP3939-010, ATGP3939-020, ATGP3939-050, ATGP3939-100, ATGP3939-250, ATGP3939-500, ATGP3939-01M
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
47.5 kDa (426aa)
Description
RANK, as known as Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A) is a member of the tumor necrosis factor receptor (TNFR) molecular sub-family. It is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It is associated with bone remodeling and repair, activation of NF-kappa B and c-jun N-terminal kinase, enhancement of T cell growth and dendritic cell function, immune cell function, lymph node development, thermal regulation, and mammary gland development. It is able to block TRANCE induced biological activity. Recombinant mouse RANK, fused to hlgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Mouse
Gene Category
Immunology, Hormones & Cytokines
Domain
31-214aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Mouse RANKL/TNFSF11 (CAT# ATGP3915). The ED50 range ≤ 200 ng/ml.
Predicted nterm
Ala
Species of Protein
Mouse
Manufacturer - Search Terms
ATGP4155-10ug, ATGP4155-20ug, ATGP4155-50ug, ATGP4155-100ug, ATGP4155-250ug, ATGP4155-500ug, ATGP4155-1mg, ATGP4155-010, ATGP4155-020, ATGP4155-050, ATGP4155-100, ATGP4155-250, ATGP4155-500, ATGP4155-01M, ATGP3939-10ug, ATGP3939-20ug, ATGP3939-50ug, ATGP3939-100ug, ATGP3939-250ug, ATGP3939-500ug, ATGP3939-1mg, ATGP3939-010, ATGP3939-020, ATGP3939-050, ATGP3939-100, ATGP3939-250, ATGP3939-500, ATGP3939-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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