Recombinant human Carbonyl reductase 3/CBR3 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Carbonyl reductase 3 (CBR3) is one of several monomeric NADPH-dependent oxidoreductases. This protein catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It also contains three exons spanning 11. 2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. Some studies suggest that it mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy. Recombinant human CBR3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Redox Proteins

Human

Carbonyl reductase 3, CBR3, NADPH-dependent carbonyl reductase, Carbonyl reductase (NADPH) 3, EC 1.1.1.184, hCBR3, Carbonyl reductase (NADPH) 3 EC 1.1.1.184, NADPH dependent carbonyl reductase 3, SDR21C2, Short chain dehydrogenase/reductase family 21C member 2.