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Mouse ADAM8 Protein (ADM-MM108)

ArtNr ADM-MM108-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Konjugat/Tag HIS
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dry ice Yes
Sequence Pro17-Ser658
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ADAM 8,Ms2,Adam8,CD156a,MGC134985
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
ADAM8
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 71.7 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Description
Recombinant Mouse ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro17-Ser658.
Background
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Supplied as 0.22μm filtered solution in 20mM Tris, 5mM CaCl2, 75mM NaCl, 50% Glycerol (pH 7.5).
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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