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Human DSG-2/Desmoglein-2 Protein (DSG-HM102)

ArtNr DSG-HM102-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS
Purity > 95% as determined by Bis-Tris PAGE
Formula Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Sequence Ala50-Gly609
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Desmoglein-2,HDGC,DSG2,CDHF5,ARVC10,CMD1BB,MGC117036,MGC117037
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
DSG-2/Desmoglein-2
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
Shipped at ambient temperature.
Storage Conditions
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Description
Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.
Background
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
lieferbar

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