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Human FGF-9 Protein, Fc Tag Europäischer Partner

ArtNr FG9-H4267-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 92%
Citations (1) Miyamoto M, er al. 1993, Mol Cell Biol 13 (7): 4251-9. (2) Santos-Ocampo S, et al. 1996, J. Biol. Chem. (UNITED STATES) 271 (3): 1726-31. (3) Chellaiah A, et al. 1999, J. Biol. Chem. (UNITED STATES) 274 (49): 34785-94.
NCBI AAI03979
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGF9,GAF,HBFG-9,MGC119914,MGC119915,SYNS3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Cytokines&Growth Factors
Manufacturer - Conjugate / Tag
N-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
50.1 kDa
Manufacturer - Format
Powder
Description
Human FGF-9, Fc Tag (FG9-H4267) is expressed from human 293 cells (HEK293). It contains AA Leu 4 - Ser 208 (Accession # AAI03979).
Background
Fibroblast growth factor 9 is also known as FGF9, GAF, HBFG-9, SYNS3, and is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF9 is also a mitogen for oligodendrocyte type 2 astrocyte progenitor cells, smooth muscle cells, pheochromocytoma PC12 cells, and BALB/3T3 fibroblasts. However, unlike FGF acidic and basic, FGF9 has no effect on human umbilical vein endothelial cells, and it has been demonstrated that FGF9 binds preferentially to the IIIc form of FGFR3. Although no typical signal sequence was found in FGF9, it is secreted efficiently after synthesis not in a conventional manner. In nervous system, FGF9 is produced mainly by neurons and may plays an important role in CNS development. FGF9 has been shown to interact with Fibroblast growth factor receptor 3.
Molecule
FGF-9
Exp Region
Leu 4 - Ser 208
Characteristics
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 50.1 kDa. The protein migrates as 55 kDa under reducing (R) condition, and 110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM Tris, 100 mM Glycine, pH 7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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