PTP alpha/PTPRA, Human (sf9, His-GST)

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PTP alpha/PTPRA Protein, a tyrosine protein phosphatase, participates in integrin-mediated focal adhesion formation. Upon integrin engagement, it recruits BCAR3, BCAR1, and CRK to focal adhesions, promoting SRC-mediated phosphorylation of BRAC1. This leads to the activation of PAK and small GTPases RAC1 and CDC42. PTP alpha/PTPRA Protein, Human (sf9, His-GST) is the recombinant human-derived PTP alpha/PTPRA protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PTP alpha/PTPRA Protein, Human (sf9, His-GST) is 620 a.a., with molecular weight of ~90 kDa.