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Recombinant human MMAB protein

ArtNr NKM-ATGP0677-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MQSRGPQGVE DGDRPQPSSK TPRIPKIYTK TGDKGFSSTF TGERRPKDDQ VFEAVGTTDE LSSAIGFALE LVTEKGHTFA EELQKIQCTL QDVGSALATP CSSAREAHLK YTTFKAGPIL ELEQWIDKYT SQLPPLTAFI LPSGGKISSA LHFCRAVCRR AERRVVPLVQ MGETDANVAK FLNRLSDYLF TLARYAAMKE GNQEKIYKKN
Citations Gravel RA., et al. (2009) Mol Genet Metab. 98(3):278-84
Edwards AM., et al (2004) J Biol Chem. 279(22):23646-53.
NCBI AAH05054
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Methylmalonic aciduria (cobalamin deficiency) cblB type,ATR,ATP:cob(I)alamin adenosyltransferase,Methylmalonic aciduria (cobalamin deficiency) cblB type
Similar products ATR, MMAB, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type, ATGP0677-10ug, ATGP0677-20ug, ATGP0677-50ug, ATGP0677-100ug, ATGP0677-250ug, ATGP0677-500ug, ATGP0677-1mg, ATGP0677-10, ATGP0677-20, ATGP0677-50, ATGP0677-100, ATGP0677-250, ATGP0677-500, ATGP0677-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
26.3 kDa (239aa) confirmed by MALDI-TOF
Description
MMAB is a protein that catalyzes the final step in the conversion of vitamin B (12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase (MCM). Impaired MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group. Recombinant human MMAB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
33-250aa
Species of Protein
Human
Manufacturer - Search Terms
MMAB, Methylmalonic aciduria (cobalamin deficiency) cblB type, ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type, ATGP0677-10ug, ATGP0677-20ug, ATGP0677-50ug, ATGP0677-100ug, ATGP0677-250ug, ATGP0677-500ug, ATGP0677-1mg, ATGP0677-10, ATGP0677-20, ATGP0677-50, ATGP0677-100, ATGP0677-250, ATGP0677-500, ATGP0677-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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