Recombinant human Protein C Inhibitor/SERPINA5 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Serpin A5, also known as PCI (Protein C Inhibitor) or PAI3 (plasminogen activator inhibitor 3), is a member of the serpin serine proteinase inhibitor family. This protein inhibits plasminogen activators as well as activated protein C. Serpin A5 is secreted in plasma, but is also expressed in liver. Serpin A5 is involved in cell inflammation, proliferation, apoptosis, tumor cell migration, invasion, and metastasis. Recombinant Serpin A5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM MES buffer (pH 6.0) containing 150mM NaCl, 10% glycerol

Cardiovascular

Measured by its ability to inhibit Thrombin cleavage of substrate Boc-VPR-AMC. The IC50 for this effect is less or equal to 2 nM

Serpin A5, Serpin peptidase inhibitor, clade A, member 5, PAI3, PCI, PROCI, ATGP3746-10ug, ATGP3746-20ug, ATGP3746-50ug, ATGP3746-100ug, ATGP3746-250ug, ATGP3746-500ug, ATGP3746-1mg, ATGP3746-10, ATGP3746-20, ATGP3746-50, ATGP3746-100, ATGP3746-250, ATGP3746-500, ATGP3746-1