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Recombinant human GalNAc Transferase 1/GALNT1 protein

ArtNr NKM-ATGP3850-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>GLPAGDV LEPVQKPHEG PGEMGKPVVI PKEDQEKMKE MFKINQFNLM ASEMIALNRS LPDVRLEGCK TKVYPDNLPT TSVVIVFHNE AWSTLLRTVH SVINRSPRHM IEEIVLVDDA SERDFLKRPL ESYVKKLKVP VHVIRMEQRS GLIRARLKGA AVSKGQVITF LDAHCECTVG WLEPLLARIK HDRRTVVCPI IDVISDDTFE YMAGSDMTYG GFNWKLNFRW
Citations Gerken, T.A. et al. (2011) J. Biol. Chem. 286:14493-14507.
Partt, M.R. et al. (2004) Chem. Biol. 11:1009-1016.
NCBI NP_065207
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Polypeptide N-acetylgalactosaminyltransferase 1,Polypeptide GalNAc transferase 1,GalNAc-T1,pp-GaNTase 1,Protein-UDP acetylgalactosaminyltransferase 1,UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1
Similar products GALNAC-T1, GALNT1, GALNT1Polypeptide N-acetylgalactosaminyltransferase 1, ATGP3850-10ug, ATGP3850-20ug, ATGP3850-50ug, ATGP3850-100ug, ATGP3850-250ug, ATGP3850-500ug, ATGP3850-1mg, ATGP3850-10, ATGP3850-20, ATGP3850-50, ATGP3850-100, ATGP3850-250, ATGP3850-500, ATGP3850-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
60.4 kDa (528aa)
Description
GALNT1, also known as polypeptide N-acetylgalactosaminyltransferase 1, is a member of the GalNAc-T family of enzymes. It utilizes UDP-GalNAc as the nucleotide donor substrate to modify serine or threonine residues of proteins trafficking through the secretory pathway. Structurally, GalNAc-Ts consist of an N-terminal catalytic domain tethered by a short linker to a C-terminal ricin-like lectin domain containing three potential carbohydrate-binding sites. Also, this protein is involved in the glycosylation of proteins essential for bone formation such as osteopontin and bone sialoprotein. Recombinant human GALNT1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
41-559aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 300pmol/min/ug, and is defined as the amount of enzyme that transfer 1.0pmole of GalNAc from UDP-GalNAc to peptide EA2 per minute per minute at pH 8.0 at 37C.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
GALNT1, GALNT1Polypeptide N-acetylgalactosaminyltransferase 1, GALNT1, GALNAC-T1, ATGP3850-10ug, ATGP3850-20ug, ATGP3850-50ug, ATGP3850-100ug, ATGP3850-250ug, ATGP3850-500ug, ATGP3850-1mg, ATGP3850-10, ATGP3850-20, ATGP3850-50, ATGP3850-100, ATGP3850-250, ATGP3850-500, ATGP3850-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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