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Recombinant human ENPP-2/Autotaxin protein

ArtNr NKM-ATGP4057-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS
Purity > 90% by SDS - PAGE
Sequence <DGS>MDSPWTN ISGSCKGRCF ELQEAGPPDC RCDNLCKSYT SCCHDFDELC LKTARGWECT KDRCGEVRNE ENACHCSEDC LARGDCCTNY QVVCKGESHW VDDDCEEIKA AECPAGFVRP PLIIFSVDGF RASYMKKGSK VMPNIEKLRS CGTHSPYMRP VYPTKTFPNL YTLATGLYPE SHGIVGNSMY DPVFDATFHL RGREKFNHRW WGGQPLWITA TKQGVKAGTF
Citations Benesch MG., et al, (2014) FEBS Letters. 588:2712-2727.
Kawagoe H., et al, (1995) Genomics. 30:380-384.
Benesch MG., et al, (2015) Journal of Lipid Research. 56:1134-1144.
NCBI NP_001035181.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2,ectonucleotide pyrophosphatase/phosphodiesterase 2,ENPP2,E-NPP 2,AUTOTAXIN,Extracellular lysophospholipase D,LysoPLD,ENPP2,ATX,PDNP2,ATX-X,NPP2,PD-IALPHA
Similar products ATGP4057-10ug, ATGP4057-20ug, ATGP4057-50ug, ATGP4057-100ug, ATGP4057-250ug, ATGP4057-500ug, ATGP4057-1mg, ATGP4057-10, ATGP4057-20, ATGP4057-50, ATGP4057-100, ATGP4057-250, ATGP4057-500, ATGP4057-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles
Molecular Weight
94.9kDa (825aa)
Description
ENPP-2, also known as Autotaxin, belongs to the ectonucleotide pyrophosphatase/phosphodiesterase (NPP) family. ENPP-2 is able to cleave the phosphodiester bond between the α and the β position of triphosphate nucleotides, acting as an ectonucleotide phosphodiesterase producing pyrophosphate , as most members of the ENPP family. It is unlike ENPP-1 and ENPP-3, has weak activity against nucleotides, but exhibits a lysophospholipase D activity which allows the formation of lysophosphatidic acid (LPA) and choline from lysophosphatidylcholine. Also, ENPP-2 and LPA are involved in numerous inflammatory-driven diseases such as asthma and arthritis. Recombinant human ENPP-2/Autotaxin, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
49-863aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 15, 000 units/mg, and defined as the amount of enzyme that hydrolyze 1nmole of bis(p-Nitrophenyl) phosphate per minute at pH8.7 at 37℃.
Predicted nterm
Asp
Species of Protein
Human
Manufacturer - Search Terms
ATGP4057-10ug, ATGP4057-20ug, ATGP4057-50ug, ATGP4057-100ug, ATGP4057-250ug, ATGP4057-500ug, ATGP4057-1mg, ATGP4057-10, ATGP4057-20, ATGP4057-50, ATGP4057-100, ATGP4057-250, ATGP4057-500, ATGP4057-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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