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Recombinant human Gankyrin/PSMD10 protein

Recombinant human Gankyrin/PSMD10 protein

ArtNr	NKM-GAN0901-20ug
Hersteller	NKMAX
Menge	20 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins SDS-PAGE
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG
Citations	umemura A., et al. (2008) Hepatology. 47(2):493-502. Chen Y., et al. (2007) Cell Res. 17(12): 1020-9
NCBI	NP_002805
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	proteasome 26S subunit non ATPase 10 (PSMD10) isoform 1,ankyrin repeat protein p28,Gankyrin,26S proteasome non-ATPase regulatory subunit 10,26S proteasome regulatory subunit p28,PSMD10.
Similar products	Gankyrin, GAN0901-10ug, GAN0901-20ug, GAN0901-50ug, GAN0901-100ug, GAN0901-250ug, GAN0901-500ug, GAN0901-1mg, GAN0901-10, GAN0901-20, GAN0901-50, GAN0901-100, GAN0901-250, GAN0901-500, GAN0901-1
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Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	24.4 kDa (226aa) confirmed by MALDI-TOF
Description	Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. Recombinant human Gankyrin was expressed in E. coli and purified by conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Cancer
Domain	1-226aa
Species of Protein	Human
Manufacturer - Search Terms	Gankyrin, GAN0901-10ug, GAN0901-20ug, GAN0901-50ug, GAN0901-100ug, GAN0901-250ug, GAN0901-500ug, GAN0901-1mg, GAN0901-10, GAN0901-20, GAN0901-50, GAN0901-100, GAN0901-250, GAN0901-500, GAN0901-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-GAN0901-20ug-datasheet.pdf

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Menge: 20 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 9 Tage sparen

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