CSK, Recombinant, Human, aa1-450, His-Tag (Tyrosine-Protein Kinase CSK, C-Src Kinase)

Blue Ice

53, 1

Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 20% glycerol.

CSK is a tyrosine-protein kinase CSK that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

Source:
Recombinant protein corresponding to aa1-450 from human CSK, fused to His-tag at N-terminus, expressed in E.coli.

Molecular Weight:
~53.1kD (473aa)

Applications:
Suitable for use in SDS-PAGE. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.