Anti-Mouse CD301 Antibody

Immunohistology - Frozen, Flow Cytometry, Immunofluorescence

Blue ice

12 months from the date of shipment when stored properly.

Purified IgG - liquid

CD301

IgG concentration 1.0 mg/ml (lot specific)

This antibody recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR).In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. This antibody also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.This antibody is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.