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TNFR2 / CD120b / TNFRSF1B Neutralizing Antibody

TNFR2 / CD120b / TNFRSF1B Neutralizing Antibody

ArtNr	10417-R00N6-200
Hersteller	Sino Biological
Menge	200 ug
Quantity options	200 ug 500 ug
Kategorie	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Primary Antibodies
Typ	Antibody Monoclonal
Clon	R00N6
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	sino
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Manufacturer - Type	Antibody
Storage Conditions	This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TNFRSF1B
Immunogen	Recombinant Human TNFR2 protein (Catalog#10417-H08H)
Purification	Protein A
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human TNFRSF1B / CD120b (rh TNFRSF1B; Catalog#10417-H08H; Met 1-Asp 257; NP_001057.1).
Specificity	Human TNFRSF1B / TNFR2 / CD120b
Buffer	0.2 um filtered solution in Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0
Endotoxin	<1.06 EU/mg
No cross-reactivity	No cross-reactivity with Mouse TNFR2 (50128-M08H) in ELISA assay
Block	This TNFR2 neutralizing antibody can block the binding of recombinant TNFa (10602-HNAE) to its recombinant receptor TNFRII(10417-H08H).
Neutralization	The neutralization activity of TNFR2/TNFRSF1B Neutralizing Antibody is Measured by its ability to neutralize TNFR2/TNFRSF1B-mediated inhibition of cytotoxicity in the L?929 mouse fibroblast cell line. The Neutralization titer (IC50) is typically 1-3 ug/mL in the presence of 1 ug/mL Recombinant Human TNFR2/TNFRSF1B, 0.25 ng/mL Recombinant Human TNFa, and 1 ug/mL actinomycin D.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

10417-R00N6-200-datasheet.pdf

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Menge: 200 ug

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