Human NRG1-beta 1 Protein (ECD, Fc Tag)

Hersteller Sino Biological
Kategorie
Typ Proteins
Specific against Human
Format Human Cell
Menge 100 ug
Host Human
ArtNr 11609-H01H2-100
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Molecule
NRG1
Synonym
ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the N-terminal fragment (Ser 2-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was fused with the Fc region of human IgG1 at the N-terminus.
Expressed Host
Human Cells
Purity
> 85 % as determined by SDS-PAGE
Bio-Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized human Erbb3-his (cat: 10201-H08H) at 10 ug/mL (100 ul/well) can bind human NRG1 (aa 2-246)-Fc, The EC50 of human NRG1 (aa 2-246)-Fc is 0.16 ug/mL.
3. Immobilized Rhesus Erbb3-his (cat: 90043-H08H) at 10 ug/mL (100 ul/well) can bind human NRG1 (aa 2-246)-Fc, The EC50 of human NRG1 (aa 2-246)-Fc is 0.37 ug/mL.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Glu
Molecule Mass
The recombinant human NRG1(aa2-246?/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 505 amino acids and has a calculated molecular mass of 55.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 75 kDa due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
Q02297-6
Amino acid sequence
Ser2-Lys246
TAG
N-human IgG1-Fc
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 192,96 €
Preis: 192,96 €
lieferbar

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