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Recombinant Human IL-17A Protein, HPLC-verified Europäischer Partner

ArtNr 12047-HNAS-5
Hersteller Sino Biological
Menge 5 ug
Quantity options 1 mg 100 ug 2 mg 4 mg 5 ug
Kategorie
Typ Proteins
Format CHO Stable Cells
Specific against Human (Homo sapiens)
Host CHO cells
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CTLA-8, CTLA8, IL-17, IL-17A, IL17
Similar products IL17A
Lieferbar
Manufacturer - Category
Protein
Molecule
IL17A
Synonym
CTLA-8, CTLA8, IL-17, IL-17A, IL17
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the mature form of human IL17A(Q16552) (Ile20-Ala155) was expressed with a N-terminal Met.
Expressed Host
CHO Stable Cells
Purity
(16.9+21.7+50.1) % as determined by SDS-PAGE
Bio-Activity
1. Measured by its binding ability in a functional ELISA. Immobilized human IL17A (cat:12047-HNAS) at 10 ug/ml (100 ul/well) can bind human IL17Ra (Cat:10895-H03H), The EC50 of human IL17Ra (Cat:10895-H03H) is 20.0-48.0 ng/ml.
2. Measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 1-4 ng/mL.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Met
Molecule Mass
The recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa. It migrates as an approximately 16, 19, and 20 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Accession
Q16552
Amino acid sequence
Ile20-Ala155
TAG
Native

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 ug
Lieferbar: In stock
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