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Recombinant Human IL-17A Protein, HPLC-verified

Recombinant Human IL-17A Protein, HPLC-verified

Item no.	12047-HNAS-5
Manufacturer	Sino Biological
Amount	5 ug
Quantity options	1 mg 100 ug 2 mg 4 mg 5 ug
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Format	CHO Stable Cells
Specific against	Human (Homo sapiens)
Host	CHO cells
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CTLA-8, CTLA8, IL-17, IL-17A, IL17
Similar products	IL17A
Available
Manufacturer - Category	Protein
Molecule	IL17A
Synonym	CTLA-8, CTLA8, IL-17, IL-17A, IL17
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the mature form of human IL17A(Q16552) (Ile20-Ala155) was expressed with a N-terminal Met.
Expressed Host	CHO Stable Cells
Purity	(16.9+21.7+50.1) % as determined by SDS-PAGE
Bio-Activity	1. Measured by its binding ability in a functional ELISA. Immobilized human IL17A (cat:12047-HNAS) at 10 ug/ml (100 ul/well) can bind human IL17Ra (Cat:10895-H03H), The EC50 of human IL17Ra (Cat:10895-H03H) is 20.0-48.0 ng/ml. 2. Measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 1-4 ng/mL.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Met
Molecule Mass	The recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa. It migrates as an approximately 16, 19, and 20 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4.
Accession	Q16552
Amino acid sequence	Ile20-Ala155
TAG	Native

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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