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Recombinant Mouse FGFR4 Protein (His & hFc Tag)

Recombinant Mouse FGFR4 Protein (His & hFc Tag)

ArtNr	50194-M03H-100
Hersteller	Sino Biological
Menge	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg 50 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Peptides & Proteins Recombinant Proteins Astrocytoma Calcium Binding Protein Markers
Typ	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	Human
Konjugat/Tag	HIS, Fc
Purity	> 95 % as determined by SDS-PAGE
Sequence	Met1-Asp366
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Fgfr-4
Similar products	FGFR4
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Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	C-human IgG1-Fc & His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	FGFR4
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Asp 366) of mouse FGFR4 (NP_032037.2) precursor was fused with the C-terminal polyhistidine tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	Measured by its ability to inhibit FGF acidic (aFGF / FGF1) dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 30-40 ng/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Leu l7
Molecule Mass	The recombinant mouse FGFR4/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 598 amino acids and has a predicted molecular mass of 67 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FGFR4/Fc monomer is approximately 100-110 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50194-M03H-100-datasheet.pdf

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Menge: 100 ug

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