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Recombinant Mouse PCSK9 Protein (His Tag), HPLC-verified

Recombinant Mouse PCSK9 Protein (His Tag), HPLC-verified

ArtNr	50251-M08H-1
Hersteller	Sino Biological
Menge	1 mg
Quantity options	1 mg 100 ug 2 mg 20 ug 4 mg
Kategorie	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins
Typ	Proteins
Specific against	Mouse (Murine, Mus musculus)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI415265, AI747682, FH3, HCHOLA3, Narc1, PC9
Similar products	PCSK9
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Protein
Shipping method	Blue ice shipping
Molecule	PCSK9
Synonym	AI415265, AI747682, FH3, HCHOLA3, Narc1, PC9
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the full length of mouse PCSK9 (NP_705793.1) precursor (Met 1-Gln 694) was expressed, with a C-terminal polyhistidine tag.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized mouse PCSK9 at 10 ug/ml (100 ul/well) can bind biotinylated recombinant human LDLR . The EC50 of biotinylated human LDLR is 0.12 ug/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Gln 35
Molecule Mass	The secreted recombinant mouse PCSK9 consists of 671 amino acids and has a calculated molecular mass of 72.6 kDa. As a result of proteolysis and glycosylation, the recombinant protein migrates as doublet with apparent molecular mass of approximately 19 & 65 kDa, cprresponding to the prodomain and the mature form of PCSK9 respectively in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 15mM Tris, 90mM NaCl, 50% Glycerol, pH 7.5
Accession	NP_705793.1
Amino acid sequence	Met1-Gln694
TAG	C-His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50251-M08H-1-datasheet.pdf

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Menge: 1 mg

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