Methanesulfonic Acid Methyl Ester

RT

110, 13

Supplied as a colorless to pale yellow, clear oil

Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine; an impurity of Lamotrigine which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.

Solubility:
DMSO (Slightly), Methanol (Slightly)

Method for Determining Identity:
Proton NMR (DMSO-d6), 13C NMR (DMSO-d6) Spectroscopic Analysis and Mass Spectrometric Analysis

Atmosphere:
Inert gas

Storage and Stability:
Powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Note: Inert atmosphere is preferred for long term storage.

Important Notes:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards:
All products should be handled by qualified personnel only, trained in laboratory procedures.